Low AMH and IVF: The Pro’s and Con’s

Ten years ago most IVF clinics refused to let women with low AMH levels use their eggs because success rates were that low. Donor eggs were the only option. A 2010 study on success rates of women with low AMH levels using their eggs are between 2% – 8% per cycle. Women with AMH levels below 1.06 ng/ml or 7.5 pmol/l fall into this category.

Success rates aren’t any better today, but most IVF clinics will allow women with low AMH levels to use their eggs now. Why is that?

It is good business for IVF clinics. Also, the medical profession believes that IVF clinics are the only ones that offer any hope. Many women don’t want a donor egg and are happy to accept the low success rates.

Are there ways to improve success rates for women with low AMH using their eggs during an IVF cycle?

It is an accepted fact that science and modern medicine has no treatment to improve egg quality for women with low AMH. There is no patented drug on the market offered by the pharmaceutical companies or the medical profession.

You may have heard of treatments offered to help improve egg quality. Has your gynecologist or IVF doctor recommended any of them? Likely not. Why?

There is no lack of science on many supplements to improve egg quality.

The reason why your doctors are unlikely to recommend them is straightforward.

Pharmaceutical companies have not been able to patent any research or science on these products. Research has not been able to improve pregnancy outcomes for women with low AMH levels.

Medical doctors (MD’s) are not permitted to recommend treatments outside of their field. The pharmaceutical companies control these recommendations under the rule of evidence-based practice. If science proves it is true, then it must be true. Medicine follows these rules as best they can.

Supplements are not considered medicine.

Doctors suggest these options on a personal, not medical, recommendation. It is the way the system operates.

Research proves that DHEA and Ovance improve pregnancy outcomes and raises AMH levels.

DHEA has unwanted side-effects, Ovance does not.

Products that contain or combine these ingredients are not supported by science. Research shows no statistical difference in pregnancy rates for women who have used them and those who have not. Opinions in social media can differ from the science that investigated them.

These include:

CoQ10

Myo-Inositol

L-Arginine

Melatonin

Vitamin D3

EPA/DHA Omega 3

Check on the product links above to know the research and science of their effectiveness.

Let’s focus on what the best options are.

It is what you do outside of the IVF clinic that improves your chances of success, not what happens in it. Using proven treatments to increase your AMH levels and enhance the quality of the egg is a smart idea. Using procedures with proven pregnancy outcomes in women with low AMH are the best.

These include only two treatments so far.

DHEA

Ovance

What are wasteful options?

If you have low AMH levels and want to undergo a “stimulated IVF cycle” you are more likely to fail than any other group. Women with low AMH are the most valuable clients of IVF. Women with low AMH have the lowest success rates but are likely to pay the most amount of money.

Natural IVF cycles offer more hope for women with low AMH. Science has shown (2) that IVF drugs decrease egg quality. This study in 2013 proved that stimulated IVF cycles lowered AMH levels. This study tested only on women with perfect AMH levels, not low AMH levels. If GnRH and FSH drugs lower AMH levels in healthy women, what does it do to women with low AMH levels?

Reports (need reference) show that repeated stimulated IVF cycles on women with low AMH yield fewer eggs every time.

What is the reason why?

The answer is simple. Your body wants balance 100% of the time. Homeostasis is the term. Know it as the equilibrium of your body. You cannot add hormones to your body without an opposite reaction from your body. Your body will reduce its hormone production when you add them artificially. Add hormones to grow more eggs than it should this cycle, and it will grow less egg next cycle without the drugs. Repeated stimulated cycles with IVF drugs down-regulate your egg producing hormones more and more.

Imagine if your work asked you to be four times more productive without any extra time or any extra pay. IVF stimulating drugs do the same thing. Why should your body produce 5 – 12 great eggs on drugs, when it cannot provide one good one in the first place?

It is the natural process of homeostasis that creates hormone down-regulation. Improving your natural cycles of hormone production is not done by adding artificial hormones.

Natural IVF. Is it a better option for women with poor egg quality?

Science proves that regular stimulated IVF cycles decrease AMH levels and therefore egg quality. Why would any woman use this method for pregnancy? Because sometimes it works. Over 90% of the time it does not.

Improving your egg quality before seeking IVF is the smartest thing to do. It will save you money and improve your chances. Most IVF doctors believe that their treatment is your only hope.

2% – 8% is still the success rate after eight years of technology and development.

Your options are straight-forward.

Believe your IVF doctor and bet on 2% – 8% per cycle with ever decreasing egg recruitment.

Try natural IVF cycles with no GnRH or FSH drugs to not disturb your AMH levels.

Use products proved to increase you AMH levels to improve egg quality. Do this before you try natural or stimulated IVF treatments.

Make sure you have investigated your supplements before you spend your money.

Don’t bank on supplements that only work on mice, but are not proven to help women.

These can be a waste of money and hope.

https://linkinghub.elsevier.com/retrieve/pii/S0015028210007053

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379743/

https://www.advancedfertilitysolutions.com/amh-what-is-it

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470079/

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