AMH and Fertility: The Pro’s and Con’s of Low AMH and IVF.

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AMH and Fertility: The Pro's and Con's of Low AMH and IVF

Success rates aren’t any better today, but most IVF clinics will allow women with low AMH levels to use their eggs now. Why is that?

IVF is the only industry in the world whose best profits are based on failure rather than success.

Are there ways to improve success rates for women with low AMH using their eggs during an IVF cycle?

Supplements are not considered medicine.

It is an accepted fact that science and modern medicine has no treatment to improve egg quality for women with low AMH levels. There is no patented drug on the market offered by the pharmaceutical companies or the medical profession as treatment for women.

You may have heard of alternative treatments or supplements offered to help improve egg quality. However, has your gynecologist or IVF doctor recommended any of them? Likely not. The reason why your doctors are unlikely to recommend alternative therapies or supplements is straightforward; pharmaceutical companies have not been able to patent any research or science on these products. Medical doctors (MD’s) are not permitted to recommend treatments outside of their field. The pharmaceutical companies control these recommendations under the rule of evidence-based practice. If science proves it is true, then it must be true. If science says the medical profession cannot help, then the conclusion is that no-one can help. Medicine follows these rules as best they can.

This page has detailed information on how to know if your pregnancy supplements will work. The information provided will help to make the informed choices when choosing alternative treatment to support you on your fertility journey.

Research proves that DHEA and Ovance & RPM improve pregnancy outcomes and raises AMH levels.

There has been much discussion as to whether people should take DHEA. Some countries banned it because it is classified as a human steroid. Most countries have now relented and let people take it. DHEA has been scientifically proven to improve pregnancy outcomes for women with diminished ovarian reserve undergoing IVF procedures. Learn more about does DHEA improve egg quality?

Ovance and RPM combination increases low AMH levels and improves egg quality. Ingredients within the Ovance and RPM combination are proven to stimulate ovarian function, promote egg production, development, and count, improves egg quality, increasing AMH levels, and overall fertility. Learn more about Ovance & RPM to improve low AMH levels and fertility.

Other supplements that are commonly used for low AMH levels – Science or Suggestion?

Products that contain or combine these ingredients are not supported by science but have a popular following. Research shows no statistical difference in pregnancy rates for women who have used them and those who have not. Opinions in forums and social media differs greatly from the science that investigated them.

CoQ10

CoQ10 and its popular brand Ubiquinol is the most consumed and probably worst construed product for improving egg quality. Women consume millions of bottles of CoQ10 and Ubiquinol a year hoping that it will improve their ovarian health and egg quality. Websites abound with the egg improving benefits of CoQ10. How can they be all wrong? Didn’t they read the science? 

There is nothing wrong with taking CoQ10 and it is not harmful (as far as any study has shown). It has been famously shown that CoQ10 levels naturally decrease in women over 30, and that by taking CoQ10 you can stem the tide of this natural decline, but not indefinitely. Learn more about CoQ10 for fertility here.

Myo-inositol

Myo-inositol naturally occurs in the body. It helps to maintain many functions and is essential for good health. Myo-inositol deficiency diagnosis is rare. Supplementing Myo-inositol can help women with insulin resistant PCOS to ovulate. It can also make up losses for people who are regularly taking antibiotics or over consume coffee. There is no evidence that Myo-inositol improves egg quality or low AMH levels. Leaern more about Myo-Inositol for pregnancy.

L-Arginine.

Our research has only uncovered inconsistent evidence about the effectiveness of L-arginine for infertility. Some early research suggests that taking 16 grams of L-arginine daily increases egg counts collected in women undergoing IVF. However, it does not seem to improve pregnancy rates. Learn more about L-Arginine and pregnancy

Melatonin

There are some significant studies on melatonin and how it can improve egg quality and preserve ovarian health in later age. On the back of these studies, melatonin is produced in labs and sold everywhere. Millions of people take it to help with their sleep but how useful is it for egg quality? Melatonin has been shown to help women’s eggs mature when undergoing IVF, but it does not improve implantation, pregnancy or miscarriage rates at all. Learn more about melatonin for pregnancy and why you should stop taking it.

VITAMIN D3  

Vitamin D3 can be a double-edged sword; too much and too little will both harm your fertility. It is proven that people and mice with vitamin D deficiency reduces their ability to breed. Same goes if you have an excess of Vitamin D. How to know if you are doing it right? Learn more about Vitamin D3 for fertility and improving egg quality.

EPA DHA Omega-3 fatty acids

In 2012 Aging Cell published a very promising study. “Prolonging the female reproductive lifespan and improving egg quality with dietary omega‐3 fatty acids.” It concluded, “omega‐3 fatty acids may provide an effective and practical avenue for delaying ovarian aging and improving oocyte quality at advanced maternal age”.


Very much like the studies on Melatonin and CoQ10, EPA/DHA Omega 3 fatty acids have the same outcome.

These studies all prove that supplementation provides longer lasting fertility in mice. If they give these supplements to mice as they age, they produce better quality eggs. Studies also show that there are higher litters of mouse pups too. Studies that show improvements in preserving egg quality for mice are not the same for women. Attempts to improve egg quality in women have shown better DNA and egg maturity. What they have not shown is an improvement in pregnancy rates in any study. Learn more about EPA DHA Omega-3 fatty acids for fertility.

Let’s focus on what the best options are.

It is what you do outside of the IVF clinic that improves your chances of success, not what happens in it. Using proven treatments to increase your AMH levels and enhance the quality of the egg is a smart idea. Using procedures with proven pregnancy outcomes in women with low AMH are the best.

These include two proven treatments so far.

DHEA

Ovance & RPM combination

What are wasteful options?

If you have low AMH levels and want to undergo a “stimulated IVF cycle” you are more likely to fail than any other group. Women with low AMH are the most valuable clients of IVF. Women with low AMH have the lowest success rates but are likely to pay the most amount of money.

Natural IVF cycles offer more hope for women with low AMH. Science has shown (2) that IVF drugs decrease egg quality. This study in 2013 proved that stimulated IVF cycles lowered AMH levels. This study tested only on women with perfect AMH levels, not low AMH levels. If GnRH and FSH drugs lower AMH levels in healthy women, what does it do to women with low AMH levels?

Reports (need reference) show that repeated stimulated IVF cycles on women with low AMH yield fewer eggs every time.

What is the reason?

The answer is simple. Your body wants balance 100% of the time. Homeostasis is the term. Know it as the equilibrium of your body. You cannot add hormones to your body without an opposite reaction from your body. Your body will reduce its hormone production when you add them artificially. Add hormones to grow more eggs than it should this cycle, and it will grow less egg next cycle without the drugs. Repeated stimulated cycles with IVF drugs down-regulate your egg producing hormones more and more.

Imagine if your work asked you to be four times more productive without any extra time or any extra pay. IVF stimulating drugs do the same thing. Why should your body produce 5 – 12 great eggs on drugs, when it cannot provide one good one in the first place?

It is the natural process of homeostasis that creates hormone down-regulation. Improving your natural cycles of hormone production is not done by adding artificial hormones.

Natural IVF. Is it a better option for women with poor egg quality?

Science proves that regular stimulated IVF cycles decrease AMH levels and therefore egg quality. Why would any woman struggling with low AMH and fertility success, use this method for pregnancy? Because sometimes it works, yet over 90% of the time it does not. 2% – 8% is still the success rate after forty years of technology, research and development.

Improving your egg quality before seeking IVF is the smartest thing to do. It will save you money and improve your chances. Most IVF doctors believe that their treatment is your only hope.

Don’t bank on supplements that only work on mice, but are not proven to help women.

Comments (6)

Cheistine Bienkowski

Hello should I take OVANCE & RPM or IVF SUPPORT prior to an ivf cycle?
also can these be taken in conjunction with DHEA

The success of IVF depends on your AMH levels. If they are low then IVF won’t work and leave you with lower AMH levels afterward.
DHEA only helps to raise Low AMH levels when they are above 1.1 ng/ml. You can use it in conjunction with the formulas we offer.

I encourage every single client to raise their AMH levels to reference range before attempting IVF. It is an expensive procedure with the lowest chance of success of any client they treat. Please read this three-part guide I wrote on IVF and Low AMH. You will not get this information from your ObGyn or IVF doctor.

https://www.advancedfertilitysolutions.com/low-amh-ivf-your-essential-guide-pt-1/

Use Ovance & RPM to raise your AMH levels, then do IVF.

Hello Christine. The formulas you take prior to IVF should depend on why you are using IVF in the first place. If you have low AMH levels, then you should have them fixed BEFORE using IVF, as IVF is most likely to fail under these circumstances. Please read the “Essential Guide to Low AMH and IVF” here to understand this issue https://www.advancedfertilitysolutions.com/low-amh-ivf-your-essential-guide-pt-1/
IVF Support combination is an excellent way to improve your overall fertility going into an IVF cycle but it does not focus on improving egg health as Ovance and RPM does.

My wife has AMH levels of 0.001, we are very worried and confused as to what to do. What do you suggest ?

Hello Yousaf, thank you for your inquiry. There are many factors that need to be considered when trying to raise AMH levels.
Most importantly is age, if a woman is 45 years old with AMH levels of 0.01 then it unlikely any medication can help her. The younger a woman is away from the end of her natural fertility life, the more possible recovery is.
Secondly FSH levels. If FSH levels are above 45 IU/L it is unlikely any medication will work. A woman’s FSH levels between 2 and 30 IU/L is a positive sign that recovery is possible.

Combining age and FSH levels can provide a good prediction of formulas required, dosages and expectations.

I recommend you visit this page, that has our research results . on it, and compare your wife’s AMH and FSH levels (on the third chart on the page) and see what her chances of recovery are https://www.advancedfertilitysolutions.com/see-the-results/

Please feel free to email me if you have more questions.
Kindest regards

Hi Dr. Scott Martin,

I am so happy to read your article as my AMH is now very low, 0.847 (ng/mL). I have got advices from many hospitals. The majority of them advised me to do IVF but one of doctor asked me to not waste money on IVF because the successful rate very low. In addition, this doctor give me some suppliments to improve quality of my ovalution before trying nature IUI (without drug). I am not sure what is different between nature IUI and nature IVF.

Could you please look a little details of my case as below and advise what the best for my next treatment.

Currently,
1. I have a little pituitary tumor (6mm). my prolactin is from 774 – 973 (uU/ml). I am taking dostinext 1 little tablet per week and my prolactin level reduce to standard or even lower than standard (i am not sure this harmful if lower than standard or not)
2. TSH: 2.760 (uU/ml)
3. FSH: 6,4 mIU/ml

Historical treatment.
First time I did IUI in early 2019 and it was sucessful but then I couldn’t keep it. The second time doctor advise me to try IVF. I tried but not succeed. The third time I tried IUI in Dec 2019 and not succeed again.

I would love to get your advice about my case.
Thank you very much!
Hoa

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